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In certain circumstancessuch as pregnancy, concurrent illness, or rapid metabolic turnoverB12 requirements may increase, and dosing adjustments may be necessary under medical supervision

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After 6 months, all patients had normal vitamin B12 concentrations

Avoid using GLP-1 RAs if you have a personal or family history of medullary thyroid carcinoma or MEN2 syndrome (Multiple endocrine neoplasia type 2 syndrome)