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Author contributions FS, NM, PF, MaK, MeK, JG, CC-S, MR, SC, VR, MV, and JR designed and performed the experiments
The absorption of vitamin B12 is fraught with hurdles: In the stomach, vitamin B12 needs to bind with a protein called Intrinsic Factor to absorb, plus sufficient acid to release it from protein foods
During the abortion process, the large amount of ROS generated increases the generation of lipid peroxidation at the maternal-fetal interface, providing a primary condition for ferroptosis
Conclusions SIBO is a central gastrointestinal complication of SSc, arising from fibrosis, dysmotility, vascular injury, and immune dysregulation