Incretin-based therapies, including GLP-1 RAs, have since expanded their therapeutic indications beyond diabetes care to weight management
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Applying four bioactive peptides to all phases simultaneously, at fixed ratios, with no feedback control, is not obviously an improvement on the bodys own regulation and no one has tested whether it helps, hurts, or does nothing
Today, GLP-1 receptor agonists are an established drug class for diabetes and obesity, and their history of development is a rich story of scientific innovation