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These findings align with previous reports that melatonin reduces ILC2-derived IL-5 and IL-13 in oxazolone-induced colitis models (65), suggesting a conserved anti-inflammatory effect of melatonin across tissues

Now, for the science bit

Human ApoE isoforms differentially modulate glucose and amyloid metabolic pathways in female brain: evidence of the mechanism of neuroprotection by ApoE2 and implications for Alzheimers disease prevention and early intervention