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Patients with conditions such as obesity, diabetes, and lipodystrophy often have low levels of serum IGF-1

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CagriSema is a two-peptide fixed combination the amylin analogue cagrilintide co-administered with the GLP-1 receptor agonist semaglutide whereas tirzepatide is a single engineered molecule that activates two receptors (GIP and GLP-1) at once