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The GIC has 460,000 members and provides insurance to state employees and their families

The enzymes returned to baseline after medication discontinuation, confirming the elevations were reversible and non-pathological in the vast majority of cases

Three amino acid-altering GIP receptor variants (R190Q, E288G, and E354Q) are all associated with lower bone mineral density, and in postmenopausal women followed for 10 years, who were homozygous carriers of the E354Q variant, showed a higher risk of non-vertebral fractures (99, 101)

While these substances offer potential benefits, their safety and efficacy are still subjects of ongoing research, and their use should be approached with caution