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Cortical superficial siderosis in CAA CAA-related bleeds include: Macrobleeds - symptomatic lobar hemorrhages Microbleeds - small and typically silent peripherally located Cortical superficial siderosis (cSS) - cortical subarachnoid hemorrhages that follow the curvilinear shape of the surrounding cerebral gyri In superficial siderosis the proximity to the cortical surface appears to be the trigger for transient focal neurologic symptoms or amyloid spells

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Materials should be handled only by qualified personnel in appropriate research facilities using established institutional procedures for biochemical reagents