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In the rat model of neuropathic pain induced by CCI, Fer-1 upregulates GPX4 expression, downregulates ACSL4 expression, and decreases the content of iron in the spinal cord, while erastin has the opposite effect

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By some measures, a dose of 1,500 mg/day was more effective than 3,000 mg/day, but by other measures the higher dose was more effective

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