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Melanotan II is a synthetic cyclic peptide and a non-selective melanocortin receptor agonist

It is often contained in sports drinks to allow athletes to refuel and rehydrate simultaneously during and after exercise

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Other studies, however, report failure of GLP-1 to directly accelerate contraction in isolated adult rat cardiomyocytes, notably despite GLP-1 stimulation of cAMP accumulation [627]

The combination of multiple medications affecting gastrointestinal motility should be carefully evaluated, and patients should be monitored for both efficacy and tolerability