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These internal MEDVi data and patient-reported outcomes do not establish that compounded semaglutide or tirzepatide are safe or effective for every patient, and they should not be viewed as a substitute for FDA-reviewed clinical trial evidence

Heres a quick look at how they stack up: The fundamental difference lies in tirzepatide's dual-receptor activity

The key regulatory milestones: FDA Breakthrough Therapy designation for MASH (September 2024) EMA PRIME designation for MASH (November 2023) China NMPA Breakthrough designation (June 2024) Phase 3 trials (SYNCHRONIZE-1 and SYNCHRONIZE-2) fully enrolled, results expected H1 of this year Estimated FDA filing: Late this year at the earliest Estimated FDA approval: Possibly next year, depending on Phase 3 results If Phase 3 results confirm Phase 2 findings, survodutide could reach the market within the next 12-24 months

What surprised me most was seeing a visible difference in just three days