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There are a few limitations with this analysis

Although food can be the source of vitamin b12, there are certain conditions that do not favor the cobalamin absorption or make it excretes out of the body in large amount

Impairment of lipid emulsion metabolism associated with carnitine insufficiency in premature infants

The meaning of this observation is quite obvious since it indicates that if energy consumption and physical stressors are too much, growth and reproductive axis maturation might not occur in the same time