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Although we focused on non-diabetic individuals with overweight and obesity, potential confounding factors such as concomitant medications, baseline gastrointestinal conditions, and varying lifestyle factors could have influenced the incidence and severity of reported adverse events

The GIP component amplifies these effects and supports better glucose handling

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[2] [14] This dual-receptor activation distinguishes it from single GLP-1 receptor agonists like semaglutide

For many people, this singlehormone therapy provides enough support to achieve meaningful progress when paired with medical guidance