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Mohiuddin MS, Himeno T, Inoue R, Miura-Yura E, Yamada Y, Nakai-Shimoda H, Asano S, Kato M, Motegi M, Kondo M, Seino Y, Tsunekawa S, Kato Y, Suzuki A, Naruse K, Kato K, Nakamura J, Kamiya H (2019) Glucagon-like Peptide-1 receptor agonist protects dorsal Root Ganglion neurons against oxidative insult

May 2025: Post-marketing research suggests that GLP-1s like Ozempic are associated with an increased risk of deep vein thrombosis (a type of blood clot)

Each sample was homogenized using a TissueLyser III (Qiagen) with 5 homogenization beads in 200 l of cold Tris lysis buffer (150 mM NaCl, 20 mM Tris, pH 7.4, 1 mM EDTA, 1 mM EGTA, 1% Triton X) containing a cocktail of protease (cOmplete Protease Inhibitor Cocktail, Roche) and phosphatase inhibitors (Phosphatase Inhibitor Cocktail 2 and 3, Sigma Aldrich), NaF and PMSF in DMSO

Hepatology (2010) 51:158492

Some people might drop a couple of pounds, while others could lose 10 pounds or much more than that