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Early studies demonstrated that when rats were treated with a different GLP-1 therapy in high dose many developed a very rare and lethal thyroid cancer called medullary cell thyroid carcinoma

Wegovy is now also approved to reduce cardiovascular (CV) event risk in people with CV disease who have obesity or are overweight

The peptide appears to maintain organ function under stress conditions through nitric oxide system modulation and vascular protection mechanisms

Regulatory Reviews and Safety Communications As observational evidence accumulated, regulators evaluated the potential safety signal

Results will vary by individual and dosage, but a review of studies found that the maximum dose (2.4 mg) showed more promising results than lower doses