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The peptide repairs intestinal mucosal damage, restores tight junction integrity reducing intestinal permeability often called leaky gut, normalizes gastric emptying and intestinal motility, protects against NSAID-induced ulcers, and promotes healing of inflammatory bowel disease lesions

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To treat patients with mild to moderate occlusive peripheral arterial disease, it is recommended that naftidrofuryl be administered orally at a dose of 300 to 600 mg/day in three divided sub-doses, swallowed whole