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In fact, Fragile X syndrome, which is caused by changes in a single gene and is associated with autistic manifestations 38,39 , has shown aberrant E/I ratios according to several lines of reports (reviewed in 40 ) in agreement with the present findings

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In June 2024, the FDA officially approved tirzepatide for the treatment of obesity-associated OSAS, marking the first GLP-1based therapy worldwide to receive this indication (16)