Ferroptosiss involvement is reinforced by the recent finding of lipid hydroperoxides in the pulmonary drainage fluid of ARDS patients ( Lipid peroxidation, the glutathione (GSH)/GPX4 axis, and iron metabolism comprise the central signaling mechanism of ferroptosis
The penetration rationale is borrowed, not AHK-Cu-specific
The HLA-DRB1*01 allele was more common in the control group and in patients with vitiligo with high serum total antioxidant capacity levels, suggesting a protective role of this allele in vitiligo [33]
Numerous studies underscore their capacity to downregulate lipogenic transcription factors (such as SREBP-1c and ChREBP), activate lipid oxidation pathways via AMPK and PPAR, enhance mitochondrial function, and reinforce antioxidant defenses through upregulation of Nrf2-mediated gene expression
Cornejo-Pareja I, Muoz-Garach A, Clemente-Postigo M, Tinahones FJ