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However, no significant changes were observed in fibrosis scores, although there was a trend toward more patients in the combination and vitamin E groups having improved fibrosis stages than in the placebo group

Zalpoor H, Bakhtiyari M, Akbari A, Aziziyan F, Shapourian H, Liaghat M, et al

Webster's Third New International Dictionary of the English Language Unabridged, Third Edition, 1971

Under normoxic conditions, for instance, CCL5 inhibits HIF-1 ubiquitination degradation while activating downstream factor ZEB1 to promote EMT and metastasis (137)