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The most common adverse events are gastrointestinal in nature, including nausea (20-47% depending on dose), constipation (21%), fatigue (20%), and vomiting (8%)

This conversion of the inactive T4 to active T3 takes place in the liver

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The drop in the average value of AOPP, from the value at T=0 to the value after 24 hours, was significant

Botch protects neurons from ischemic insult by antagonizing Notch-mediated neuroinflammation