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The crucial role of IGF-I in the development and function of Leydig cells was obtained from studies in IGF-I knockout mice[124]
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J Biol Chem 281:1742017431 Michelet F, Gueguen R, Leroy P, Wellman M, Nicolas A, Siest G (1995) Blood and plasma glutathione measured in healthy subjects by HPLC: relation to sex, aging, biological variables, and life habits