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DOI: Published online: October 24, 2017 1 Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea

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GLP-1 reduces food cravings partially by decreasing activity to the anticipation of food in the left insula of obese patients with diabetes and may inhibit over- eating by increasing activity to the consumption of food in the right OFC of obese and left insula of obese with diabetes. The study concluded: Current preclinical studies support the view that GLP-1 can be a target for reward system related disorders. Lost 80 pounds & alcohol urge Washington state attorney Erin Bradley McAleer became an instant celebrity when insider.com reported him as the man who lost 80 pounds (36.2kg) on a game changer weight-loss drug and also lost his desire to drink alcohol

In a 46-week obesity treatment trial, mean weight loss was 14.9% at the highest dose