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Glucosuria also enhances gluconeogenesis and ketogenesis, part of an SGLT2 inhibitor induced shift to a fasting state. Ketogenesis is hypothesized to be a direct mediator of cardioprotection with SGLT2 inhibition since ketone bodies are an efficient energy source with the potential to improve myocardial energy dynamics and exert direct anti-inflammatory effects [1820]

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Appl Microbiol Biotechnol 66:233242 Li W, Li Z, Ye Q (2010) Enzymatic synthesis of glutathione using yeast cells in two-stage reaction

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Several rounds of 2D classification were performed with selected classes

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