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Of those 3, one patient had a previous diagnosis of bipolar disorder

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The continuous use approach represents traditional treatment strategy where daily GHK-Cu application continues indefinitely or until goals achieved, then potentially reduces to maintenance frequency (every other day or few times weekly) rather than complete discontinuation

Aydin et al

Giugliano D, Scappaticcio L, Longo M, Caruso P, Maiorino MI, et al