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These methods enable deeper exploration of the molecular foundations of depression [377]

For most individuals, occasional IV therapy for a hangover after a night of drinking alcohol is perfectly safe

Gut microbiota-brain axis in depression: the role of neuroinflammation

Combining selenium-rich foods with vitamin D sources improves thyroid hormone metabolism, whilst zinc supports selenium-dependent enzyme function

In the sections that follow, we build on this conceptual framework to examine how major proteostasis machineries contribute to cellular and organ-level resilience and how their failure drives pathology across cardiovascular, cancer, metabolic, neurodegenerative and autoimmune disorders and highlight therapeutic strategies aimed at reinforcing proteostasis resilience