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2 Changes over time of estimated glomerular filtration rate and liver parameters

The documented starting dose is 100 mcg per dose, administered 13 times daily on an empty stomach

These drugs change how your brain works, making people want food less, especially unhealthy food

doi: 10.1016/j.freeradbiomed.2019.01.016 247 SchmittB.VicenziM.GarrelC.DenisF

If you need to continue increasing beyond 7.5 mg, maintain four-week intervals between increases (7.5 mg to 10 mg, then 10 mg to 12.5 mg, then 12.5 mg to 15 mg)