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Song J, Ren P, Zhang L, Wang XL, Chen L, Shen YH

n-Electrode three-dimensional liquid chromatography with electrochemical detection for determination of neurotransmitters

You would never know by looking at it, because the solution might still appear clear, but the biological activity would be degraded

Vascular aging has systemic consequences, affecting multiple organs by promoting oxidative stress, endothelial dysfunction, cellular senescence [44, 68, 69] and apoptosis [70], impaired angiogenesis [62, 71], morphological alterations of endothelial cells [72], and altered vasoregulatory mechanisms [73], ultimately leading to reduced perfusion and metabolic dysregulation [58, 74, 75]