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32 The primary outcome for the trial was the first occurrence of a major adverse cardiovascular event (death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke)

Structurally, Retatrutide is derived from the glucagon peptide backbone and incorporates targeted amino acid substitutions that improve resistance to enzymatic degradation while maintaining receptor binding capability

Animal and preliminary human studies indicate that GLP-1RAs may also have neuroprotective properties that could mitigate optic nerve damage (12)

Chem Eng J, 2023, 452: 139108 Cheng L, Wang X, Gong F, et al

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