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Researchers have developed dry powder inhalation systems and VIP conjugated with alpha-alumina nanoparticles (alpha-AN-VIP) that significantly reduced eosinophil counts, serum IgE, Th2 cytokines, and airway hyperresponsiveness in asthmatic animal models

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Neuroinflammation in migraine Neuroinflammation refers to an inflammatory reaction within the CNS, regulated by cytokines, chemokines, reactive oxygen species (ROS), and secondary messengers such as nitric oxide (NO) and prostaglandins (37)