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Here, using plasma metabolomics and quantitative gut microbiome profiling 16 combined with extensive confounder-control in metabolically healthy controls ( n = 275) of the MetaCardis study 6,17,18,19 , we identify gut microbial markers related to estimated glomerular filtration rate (eGFR) and plasma pro-atrial natriuretic peptide (proANP) levels, revealing a gut microbiome-kidney-heart axis (Fig

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12mg (week 17+): Despite being the highest dose, many researchers report that the transition from 8mg to 12mg produces fewer new side effects than the jump to 8mg