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Animal models treated with GLP-1 RAs demonstrate a significant reduction in plasma LPS levels and attenuated intestinal tissue inflammation, reflecting a combined effect of a restored microbiota and direct intestinal GLP-1R signaling (103, 104)

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Safety: This reclassification acknowledges the safety data presented in recent years and ensures that patients can access these tools through regulated, high-quality pharmaceutical channels rather than unregulated sources

(10) The compound is thought to potentially elevate fat pad weights in proportion to total body mass

Update 23 , 390408 (2017)