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You need to get it through a doctors prescription and use it while being watched over by healthcare experts

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As genetic variants are determined at conception they are much less affected by the confounders that can bias conventional observational studies, such as socioeconomic position, so MR studies minimize confounding

However, these agents are associated with increased thyroid cancer risk, and the packaging for these medications in the United States has a boxed warning stating that they are contraindicated in people with a personal or family history of medullary thyroid cancer and in patients with a diagnosis of multiple endocrine neoplasia syndrome type 2

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